Changing one character caused some issues back in the day with files going corrupt. Careful. This can also make things much slower as Dynamo is going to go unpacking all of those base 64 encoded base 64 encoded GUID values and then going looking for them in Revit. A stable method is to clean the bindings out of the file entire in the text editor (everything in the bindings key of the json file can be deleted, but you need to keep the key and that it is a string), as described in this post and the associated AU session and you’ll get better performance.
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