You’ll either have to set the active work plane before running the script or specify the work plane in the creation of the family. The latter would likely use this method: http://www.revitapidocs.com/2018/be4b822c-829a-7e7b-8c03-a3a324bfb75b.htm
import clr
clr.AddReference('RevitNodes')
import Revit
clr.ImportExtensions(Revit.GeometryConversion)
from Revit.Elements import *
clr.AddReference('System')
from System.Collections.Generic import *
clr.AddReference('RevitAPI')
from Autodesk.Revit.DB import *
clr.AddReference('RevitServices')
import RevitServices
from RevitServices.Persistence import DocumentManager
from RevitServices.Transactions import TransactionManager
doc = DocumentManager.Instance.CurrentDBDocument
uiapp = DocumentManager.Instance.CurrentUIApplication
app = uiapp.Application
#The inputs to this node will be stored as a list in the IN variables.
dataEnteringNode = IN
symbol = UnwrapElement(IN[0])
refPlane = UnwrapElement(IN[1])
location = UnwrapElement(IN[2])
referenceDirection = UnwrapElement(IN[3])
out = []
symbol.Activate()
reference = Reference(refPlane)
TransactionManager.Instance.EnsureInTransaction(doc)
new = doc.Create.NewFamilyInstance(reference,location.ToXyz(),referenceDirection.ToXyz(),symbol)
TransactionManager.Instance.TransactionTaskDone()
#Assign your output to the OUT variable.
OUT = new